Mother Nature has some wicked tricks. Sometimes you see pictures ore movies of baby’s, children and grown-ups that makes you wonmder what happend to these freaks of nature.

Harlequin type ichthyosis.

Harlequin-type ichthyosis (also harlequin ichthyosis, ichthyosis congenita, or keratosis diffusa fetalis), a skin disease, is the most severe form of congenital ichthyosis, characterized by a thickening of the keratin layer in fetal human skin. In sufferers of the disease, the skin contains massive, diamond-shaped scales, and tends to give off a reddish color. In addition, the eyes, ears, mouth, and other appendages may be abnormally contracted. The scaly keratin greatly limits the child’s movement. Because the skin is cracked where normal skin would fold, it is easily pregnable by bacteria and other contaminants, resulting in serious risk of fatal infection. Sufferers are known as harlequin fetuses, harlequin babies, or harlequins.

The harlequin-type designation comes from both the baby’s apparent facial expression and the diamond-shape of the scales (resembling the costume of Arlecchino), which are caused by severe hyperkeratosis. The disease can be diagnosed in the uterus by way of fetal skin biopsy or by morphologic analysis of amniotic fluid cells obtained by amniocentesis. In addition, doctors can now usually recognize common features of the disease through ultrasound, and follow up with 3D ultrasound can diagnose the condition.

In the past, the disorder was invariably fatal, whether due to dehydration, infection (sepsis), restricted respiration due to the plating, or other related causes. The most common cause of death was systemic infection and sufferers rarely survived for more than a few days. However, there have been improvements in care, most notably the drug Isotrex. Some patients have survived into adolescence and, in very rare cases, lived to adulthood.

Mother Nature has some wicked tricks. Sometimes you see pictures ore movies of baby’s, children and grown-ups that makes you wonmder what happend to these freaks of nature.

Tree man

An Indonesian fisherman who feared that he would be killed by tree-like growths covering his body has been given hope of recovery by an American doctor - and Vitamin A.
Dede, now 35, baffled medical experts when warty “roots” began growing out of his arms and feet after he cut his knee in a teenage accident.
The welts spread across his body unchecked and soon he was left unable to carry out everyday household tasks. Sacked from his job and deserted by his wife, Dede has been raising his two children - now in their late teens - in poverty, resigned to the fact that local doctors had no cure for his condition. To make ends meet he even joined a local “freak show”, parading in front of a paying audience alongside victims of other peculiar diseases. Although supported by his extended family, he was often a target of abuse and ridicule in his rural fishing village.

But now an American dermatology expert who flew out to Dede’s home village south of the capital Jakarta claims to have identified his condition, and proposed a treatment that could transform his life. After testing samples of the lesions and Dede’s blood, Dr Anthony Gaspari of the University of Maryland concluded that his affliction is caused by the Human Papilloma Virus (HPV), a fairly common infection that usually causes small warts to develop on sufferers.
Dede’s problem is that he has a rare genetic fault that impedes his immune system, meaning his body is unable to contain the warts. The virus was therefore able to “hijack the cellular machinery of his skin cells”, ordering them to produce massive amounts of the substance that caused the tree-like growths known as “cutaneous horns” on his hands and feet. Dede’s counts of a key type of white blood cell are so low that Dr Gaspari initially suspected he may have the Aids virus. But tests showed he did not, and it became clear that Dede’s immune condition was something far rarer and more mysterious.

Warts aside, he had enjoyed remarkable good health throughout his life - which would not be expected of someone with a suppressed immune system - and neither his parents nor his siblings have shown signs of developing lesions. “The likelihood of having his deficiency is less than one in a million.” Dr Gaspari, who became involved in the case through a Discovery Channel documentary, believes that Dede’s condition can be largely cleared up by a daily doses of a synthetic form of Vitamin A, which has been shown to arrest the growth of warts in severe cases of HPV.

“He won’t have a perfectly normal body but the warts should reduce in size to the point where he could use his hands,” Dr Gaspari said. “Over the course of three to six months the warts should be come smaller and fewer in number. He will be living a more normal life.” The most resilient warts could then be frozen off and the growths on his hands and feet surgically removed. Dr Gaspari hopes to get the necessary drugs free of charge from pharmaceutical firms. They would then be administered by Indonesian doctors under his supervision. Still intrigued by the origins of Dede’s peculiar immune condition, the doctor would like to fly him to the United States for further examination, but fears the financial and bureaucratic barriers would prove too difficult to overcome. “I would like to bring him to the US to run tests on where his immune condition has come from, but I would need funding and to get him a visa as well as someone to cover the costs of the tests,” he said. “I’ve never seen anything like this in my entire career.”

Mother Nature has some wicked tricks. Sometimes you see pictures ore movies of baby’s, children and grown-ups that makes you wonmder what happend to these freaks of nature.

Anencephaly

Anencephaly is a cephalic disorder that results from a neural tube defect that occurs when the cephalic (head) end of the neural tube fails to close, usually between the 23rd and 26th day of pregnancy resulting in the absence of a major portion of the brain, skull, and scalp. Children with this disorder are born without a forebrain, the largest part of the brain consisting mainly of the cerebral hemispheres (which include the isocortex, which is responsible for higher level cognition, i.e., thinking). The remaining brain tissue is often exposed - not covered by bone or skin.
A baby born with anencephaly is usually blind, deaf, unconscious, and unable to feel pain. Although some individuals with anencephaly may be born with a rudimentary brain stem, the lack of a functioning cerebrum permanently rules out the possibility of ever gaining consciousness. Reflex actions such as breathing and responses to sound or touch may occur.

In India babies get a flying start. There is a ritual in India to make sure your baby will have a good health during the rest of their lives. The ritual however seems a health risk itself. People climb on the roof of a fairly high building and then drop the baby. On the ground some people are wainting with a blanket.
They say that it isn’t dangerous, because nothing has happened… yet.

A sixth human foot, wearing an Adidas training shoe, bobbed ashore near Vancouver yesterday in a grisly mystery that has gripped Canada.

The discovery of five right feet and one left foot has spawned wildly contrasting theories about their origin, ranging from murders by biker gangs to the floating remains of Asian tsunami victims.

Police are focusing on a possible link to a plane crash in the area in February 2005, from which four men are still missing. But it is also possible the feet come from suicide victims or fishermen who went overboard off Alaska.

At least five of the feet were wearing training shoes that appear to have kept them afloat, protecting them from the salt water.

“This one stretches everyone’s imagination, but we really need to remember that these remains are someone’s loved one. I’m reluctant to treat this as some sort of crime thriller,” said Terry Smith, the chief coroner of British Columbia.

The feet have all been found on islands in the Strait of Georgia, off Vancouver, near the mouth of the Fraser River. The first foot was found last August by a girl playing on a remote beach on Jedidah Island, who picked up the size 12 white training shoes and undid the laces to check inside.

All the feet were found in the Strait of Georgia

Six days later, a woman hiking on nearby Gabriola Island came upon another size 12 training shoe — also a right foot. Two more right feet were found on February 8 on Valdes Island and on May 22 on Kirkland Island.

The first left foot was recovered on Monday on nearby Westham Island when two people out walking their dog pulled a shoe from the water.

The sixth foot was found on a beach in Vancouver Island inside a size 10 black Adidas shoe yesterday morning.

The Royal Canadian Mounted Police, seeking to allay fears of a serial killer, says there is no evidence the feet were cut off.

DNA tests have been conducted on family members of four men whose sea-plane crashed in February 2005 to determine if the remains come from their loved ones.The pilot, Arnie Feast, Fabian Bedard, and brothers Doug and Trevor DeCock went missing when they crashed near Quadra Island, about 150 miles northwest of Vancouver. The body of the fifth man on the plane later washed up.

Bodies come apart at the joints when submerged in water for some time, and flesh begins to change into adipocere tissue, a soap-like substance sometimes called “grave wax” that crabs and microbes will eat, experts say.

Curtis Ebbesmeyer, a Seattle-based oceanographer, said that it was very strange that only feet had washed ashore.

“Running shoes mostly float, but half of all bodies float naturally,” he said. “The specific gravity of humans is about equal to water. You talk to your friends: some know if they are sinkers; others known they are floaters. Heads float too, so you would expect to find other remains. It’s obviously very puzzling.”